Mitral valve prolapse is a structural abnormality of the mitral valve that arises when part of its supporting apparatus—such as the leaflets, chordae tendineae, or papillary muscles—undergoes changes leading to altered valve function. These changes, often due to increased leaflet and chordal flexibility, elongation, or redundancy, cause one or both valve leaflets to bulge backward into the left atrium during systole. The condition is most frequently linked to myxomatous degeneration of the leaflets and chordae. The severity of associated mitral regurgitation depends on how much the prolapse interferes with proper leaflet coaptation. While mitral valve prolapse can occur without an identifiable cause, it is also seen in several inherited disorders, typically autosomal dominant or X-linked, such as Marfan syndrome, Ehlers-Danlos syndrome, adult polycystic kidney disease, osteogenesis imperfecta, pseudoxanthoma elasticum, systemic lupus erythematosus, polyarteritis nodosa, and muscu...
Dr. Usman's Cardiology Notes
Cardiology Notes: Clinical Cases including ECG, Echocardiography, Cath, and MOCK Exams to sharpen your cardiology data interpretation skills. Healthcare is stressful!!! Learning cardiology shouldn't be !!!